Efficient Pd(0)-mediated microwave-assisted arylation of 2-substituted imidazo[1,2-a]pyrimidines.
نویسندگان
چکیده
A short and practical synthesis of 2,3-substituted imidazo[1,2-a]pyrimidines, based on microwave-assisted Heck-type arylation of 2-substituted imidazo[1,2-a]pyrimidines, was developed. A 45-membered library of 2,3-substituted imidazo[1,2-a]pyrimidines was obtained with good yields and purities using this optimized protocol.
منابع مشابه
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ورودعنوان ژورنال:
- Journal of combinatorial chemistry
دوره 8 5 شماره
صفحات -
تاریخ انتشار 2006